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Off-the-shelf injectable adipose matrix proves a worthy filler alternative

Article-Off-the-shelf injectable adipose matrix proves a worthy filler alternative

Sponsored by MTF Biologics

Renuva® Allograft Adipose Matrix from MTF Biologics (Edison, N.J.) is a novel, off-the- shelf extracellular matrix made from donated allograft tissue that is catching on with aesthetic practitioners. This allograft product serves as a framework to support cellular repopulation and vascularization at the surgical site. It comprises the same growth factors, collagen and other elements found in adipose tissue, and can be used in various cosmetic procedures.

Intended for the replacement of damaged or inadequate integumental adipose tissue matrix, Renuva Allograft Adipose Matrix may also provide reinforcement or supplemental support to the underlying adipose tissue matrix as the result of damage or naturally occurring defects.

For the physician that has historically relied on fillers and fat grafting, Renuva has introduced an all-natural option. “There’s nothing else like it,” expressed Nima Naghshineh, MD, MSc, a plastic and reconstructive surgeon in Beverly Hills, Calif. “The matrix has no lipid or oil components, and no DNA component, but it comes with all the needed support structure to grow fat.”

One of the earliest adopters of Renuva, Michael Gold, MD, a Nashville, Tenn.- based cosmetic dermatologist, has been conducting clinical trials and found the product to be quite long lasting. “Some of my patients are one or two years out now and they are doing really well,” he said. “The results are incredibly promising. You can use it in the face where there is a lot of volume deficit, but I use it a lot in the buttocks, thighs, upper arms and any place you have lipoatrophy.”

According to Farzad R. Nahai, MD, a plastic surgeon in Atlanta, Ga., Renuva has been popular with patients that are ‘filler experienced’. “These patients have had fillers in their temples and cheeks before, they know how it works, and I tell them this is a treatment we can do every one or two years,” he expressed.

Other applications have been equally successful, added Dr. Nahai. “For the very fit, trim people that don’t have a lot of fat on their bodies, but are starting to show age in the face, I don’t have many choices with fat grafting, but Renuva is a very good option.”

Likewise, Dr. Naghshineh has used Renuva for different applications, “which is very attractive to a physician,” he stated. “There is some good evidence to show that Renuva improves skin texture and tone, as well as discoloration. For instance, I had a patient with a thyroidectomy scar on her neck – a little dimple. After I filled it with Renuva she asked me to inject more across her lower neck. She came back two or three months later and her neck’s skin tone and texture looked so much better.”

Dr. Nahai reflected on Renuva’s potential. “This is an off-the-shelf tissue solution and it truly works well. I can avoid the inconvenience and downtime of a fat graft donor site. That is a win-win for the patient and the surgeon. Renuva represents the future,” he said.

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