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Selphyl boosts blood vessel growth in fat grafts

Article-Selphyl boosts blood vessel growth in fat grafts

Wayne, N.J. — Selphyl (platelet-rich fibrin matrix, Aesthetic Factors) has been linked to an increase in blood vessels when used in combination with fat grafting procedures, a new study reports.

Aesthetic Factors, based here, examined the efficacy of the company’s Selphyl system, which has been shown to promote tissue regeneration, in improving the longevity of potential of fat transfer. PRNewswire reports that the study, headed by cosmetic surgeon Richard Goldfarb, M.D., Langhorne, Pa., involved a 37-year-old woman who had had fat from her outer thighs injected into two sites in the lower abdominal area. Investigators injected 8 ccs of fat into one site and 8 ccs of fat combined with 4 ccs of Selphyl into the other.

Researchers analyzed the tissue after eight weeks and found viable fat in both sites. The Selphyl site, however, showed an increase in blood vessels — a key to improving the chances of long-term fat survival.

“The result of this case study indicates that fat mixed with Selphyl may improve graft survival by increasing both neovascularization and total cell number,” the authors wrote in the study abstract.

The study appears in the American Journal of Cosmetic Surgery.

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