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 (Top panel) Unretouched photos at baseline and week 6 of coffeeberry regimen (left) Before and after of 54-year-old smoker with improved appearance of skin pigmentation, enhanced skin tone and improved appearance of fine lines and wrinkles, especially around the eyes. (right) Before and after of 70-year-old nonsmoker exhibiting improved appearance of skin pigmentation, reduced appearance of redness, improved appearance of fine lines and wrinkles. (Bottom panel) Unretouched photos at baseline and week 12 of coffeeberry regimen (left) Before and after of 65-year-old nonsmoker with improved appearance of fine lines, wrinkles and skin pigmentation. (right) Before and after of 51-year-old nonsmoker showing improved appearance f skin pigmentation and redness. (Photo credit: David H. McDaniel, M.D. and Zoe Diana Draelos, M.D.) |
The unique mix of antioxidants patented and marketed as "coffeeberry," are the key ingredients in a new line of skin care products called RevaleSkin (Stiefel). Early studies indicate that the product can improve wrinkles and fine lines, enhance skin tone and improve skin pigmentation from sun exposure.
POWER PACKED Coffeeberry is a mix of four polyphenols: chlorogenic acid, condensed proanthocyanidins, quinic acid and ferulic acid. The compounds are at their peak concentration when the fruit is harvested at a pre-ripe growth stage, says David McDaniel, M.D., director of the Institute of Anti-Aging Research and assistant professor of clinical dermatology and plastic surgery at the Eastern Virginia Medical School, Virginia Beach, Va. "The entirety of the coffee berry, including the whole fruit — the skin, pulp and bean, is harvested in the green and ripe stage because that's when it's at its peak antioxidant power," notes Dr. McDaniel, who has conducted research on coffeeberry.
Stiefel reports that coffeeberry dramatically outperforms other antioxidants such as green tea and vitamin C on the Oxygen Radical Absorbance Capacity (ORAC) assay developed by the U.S. Department of Agriculture to evaluate the oxygen radical absorbance capacity of food substances.According to the company, coffeeberry extract has a minimum ORAC score of 15,000, compared with green teas, which score 1,200 to 11,000; fruits, which score 104 to 5,770; and vegetables, which score 150 to 1,770.
"It's probably the most potent natural antioxidant, based on the ORAC standards," Dr. McDaniel tells Cosmetic Surgery Times .
In testing the efficacy of coffeeberry in the RevaleSkin three-step skin care product line, Dr. McDaniel conducted a six-week, double-blind clinical trial, and he says the product showed impressive results.
The study involved 30 women between 30 and 70 years of age with moderate to severe photoaging. Ten were randomly selected to participate in a split-face protocol, with the rest receiving full-face treatment. Both groups had left, right and full-face views photographed at baseline, week three and week six.
