|
 Dr. Khoury |
Case in point, some studies have shown that periocular Botox treatment enhances the aesthetic improvements attained with intense pulsed light (IPL). In 2004, researchers examined combined Botox and light treatments, versus light treatments alone¹ and found that there was a synergistic effect when the two modalities were used in combination.
 Dr. Goldman |
STUDY SPECIFICS Fifteen females ages 33 to 59 were enrolled onto this prospective, randomized, double-blind, split-face study (14 completed; one was lost to follow-up). All patients received standard IPL treatment (one pass of full-face IPL) and were randomly assigned to receive eight 0.1-mL intradermal injections of Botox in one cheek (8 U total dose) and eight injections of saline in the contralateral cheek. Injections were placed approximately 2 cm apart.
The IPL consisted of a double pulse of 3.0/4.0 ms duration with a 560 nm cut-off filter; delay times of 10 ms to 30 ms, depending on the patient's skin type; and treatment fluence of 16 J/cm2 to 17 J/cm2 with the standard 20 mm x 50 mm crystal.
 (Far left) before and (left) four weeks after IPL/Botox treatment |
After delivery of the IPL, a blinded physician was given pre-prepared, identical-looking syringes that were injected into the cheeks with a total of eight injections of each patient's assigned treatment: 0.1-mL nonpreserved sterile isotonic saline solution in one cheek, and 0.1 mL Botox (1 U/0.1 mL) for a total dose of 8 U in the other cheek.
 (Right) before and (far right) four weeks after IPL/saline treatment. Photo credit: Jane G. Khoury, M.D. |
